5 Simple Statements About pkrrating Explained
The activated enzyme then phosphorylates its key substrate, the translational initiation factor eIF2α. The ensuing translational arrest website blocks viral replication. PKR belongs into a conserved relatives of 4 protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in reaction to distinctive stimuli12, triggering the built-i